My rule of forefinger, er thumb, is not to publish Fri after 2pm PT ... and not to publish Sat after about 1 or 2 PT. I do think Tues - Fri mornings are best. But I've had successes publishing Sat and Sun morning too. I'm aiming for about 75 and up to 400 reads on pieces ... so I can certainly get 60 to 75 reads on a weekend morning to afternoon.